MTMR6 antibody (C-Term)

Catalog No. ABIN2789053

Product Details anti-MTMR6 Antibody

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Binding Specificity: C-Term

Reactivity: Human, Rat, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KDLESKIKQR KNKQTDGILT KELLHSVHPE SPNLKTSLCF KEQTLLPVND

Predicted Reactivity: Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MTMR6. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTMR6

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Alternative Name: MTMR6 (MTMR6 Products)

Synonyms: 4022440C11Rik antibody, AI428804 antibody, AU041072 antibody, zgc:55289 antibody, wu:fi04a11 antibody, si:dkey-286f3.1 antibody, zgc:56405 antibody, myotubularin related protein 6 antibody, myotubularin related protein 8 antibody, MTMR6 antibody, Mtmr6 antibody, mtmr6 antibody, mtmr8 antibody

Background: MTMR6 phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells.
Alias Symbols: -
Protein Interaction Partner: MTMR9, AMOTL2, MTUS2, NMI, TRIM27, UBC, RARG, UBD, ELAVL1,
Protein Size: 621

Molecular Weight: 68 kDa

Gene ID: 9107

NCBI Accession: NM_004685, NP_004676

UniProt: Q9Y217

Pathways: Inositol Metabolic Process