SRI antibody (Middle Region)
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- Target See all SRI Antibodies
- SRI (Sorcin (SRI))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SRI antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KELWAVLNGW RQHFISFDTD RSGTVDPQEL QKALTTMGFR LSPQAVNSIA
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Sheep: 93%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against SRI. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product SRI Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 198 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SRI (Sorcin (SRI))
- Alternative Name
- SRI (SRI Products)
- Synonyms
- zgc:64070 antibody, sri antibody, SRI antibody, CP-22 antibody, CP22 antibody, SCN antibody, V19 antibody, 2210417O06Rik antibody, 2900070H08Rik antibody, Sor antibody, sorcin antibody, Sorcin antibody, sorcin L homeolog antibody, sorcin S homeolog antibody, SRI antibody, sri antibody, EDI_060410 antibody, EDI_160670 antibody, EDI_002860 antibody, EDI_076560 antibody, CpipJ_CPIJ004933 antibody, CpipJ_CPIJ008581 antibody, Tsp_05707 antibody, sri.L antibody, sri.S antibody, Sri antibody
- Background
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SRI is a calcium-binding protein that modulates excitation-contraction coupling in the heart. It contributes to calcium homeostasis in the heart sarcoplasmic reticulum. It modulates the activity of RYR2 calcium channels.
Alias Symbols: FLJ26259, SCN, CP22
Protein Interaction Partner: PRR13, CALCOCO2, TCF12, PDE4C, GCA, STAT3, SRI, HAUS2, UBC, SRPK2, VCAM1, SMAD2, ITGA4, FN1, SNCA, SHBG, NRAS, RUVBL1, ANXA11, PSEN2, ANXA7, RYR2, CACNA1S, CACNA1C, ALG2,
Protein Size: 198 - Molecular Weight
- 22 kDa
- Gene ID
- 6717
- NCBI Accession
- NM_003130, NP_003121
- UniProt
- P30626
- Pathways
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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