MAEA antibody (N-Term)

Catalog No. ABIN2789858

Product Details anti-MAEA Antibody

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RFRAAQKNID RETSHVTMVV AELEKTLSGC PAVDSVVSLL DGVVEKLSVL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MAEA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAEA

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Alternative Name: MAEA (MAEA Products)

Synonyms: emp antibody, emlp antibody, pig5 antibody, hlc-10 antibody, MGC81431 antibody, MAEA antibody, MGC64455 antibody, MGC89777 antibody, EMLP antibody, EMP antibody, GID9 antibody, HLC-10 antibody, PIG5 antibody, 1110030D19Rik antibody, Gid9 antibody, wu:fb20a09 antibody, zgc:63708 antibody, macrophage erythroblast attacher S homeolog antibody, macrophage erythroblast attacher antibody, macrophage erythroblast attacher L homeolog antibody, maea.S antibody, MAEA antibody, maea antibody, Maea antibody, maea.L antibody

Background: This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes, this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Alias Symbols: EMLP, EMP, HLC-10, PIG5
Protein Interaction Partner: UBC, CLIP1, SOX2, FLOT1, RMND5A, GID8, UBD, RANBP9, MKLN1, GRK5, MYOC,
Protein Size: 355

Molecular Weight: 40 kDa

Gene ID: 10296

NCBI Accession: NM_005882, NP_005873