IPO7 antibody (C-Term)
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- Target See all IPO7 Antibodies
- IPO7 (Importin 7 (IPO7))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Cow, Rat, Dog, Horse, Guinea Pig, Rabbit, Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IPO7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NVIQKMICEY SEEVTPIAVE MTQHLAMTFN QVIQTGPDEE GSDDKAVTAM
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against IPO7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product IPO7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1038 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IPO7 (Importin 7 (IPO7))
- Alternative Name
- IPO7 (IPO7 Products)
- Synonyms
- fb33d09 antibody, wu:fb33d09 antibody, zgc:66425 antibody, zgc:76878 antibody, imp7 antibody, ranbp7 antibody, Imp7 antibody, RANBP7 antibody, A330055O14Rik antibody, C330016G14 antibody, Ranbp7 antibody, importin 7 antibody, importin 7 S homeolog antibody, importin-7 antibody, karyopherin antibody, ipo7 antibody, ipo7.S antibody, IPO7 antibody, CpipJ_CPIJ002096 antibody, PTRG_08544 antibody, SJAG_03693 antibody, NAEGRDRAFT_71372 antibody, VDBG_01971 antibody, MGYG_08162 antibody, Tsp_01943 antibody, Tsp_01946 antibody, Ipo7 antibody
- Background
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The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.
Alias Symbols: FLJ14581, Imp7, MGC138673, RANBP7
Protein Interaction Partner: SUMO2, SUMO3, STAU1, RNF2, rev, TNPO1, KARS, HSPA1L, HARS, APEH, PFDN5, NFRKB, ELAC2, CAND1, TRMT112, HSPA4L, RNASEH2A, FBXO6, EGFR, SOX2, METTL18, UBC, CFTR, CA9, IGBP1, RAN, CDK2, FBXO25, SIRT7, RNF146, MYC, AIRE, USP49, RPL23A, RPS7, RPL5, KPNB1, SRP19
Protein Size: 1038 - Molecular Weight
- 119 kDa
- Gene ID
- 10527
- NCBI Accession
- NM_006391, NP_006382
- UniProt
- O95373
- Pathways
- Protein targeting to Nucleus
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