PDGFRL antibody (N-Term)

Catalog No. ABIN2790370

Product Details anti-PDGFRL Antibody

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVKPKIPKMK DRDSANSAPK TQSIMMQVLD KGRFQKPAAT LSLLAGQTVE

Predicted Reactivity: Cow: 75%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PDGFRL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDGFRL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 375 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL (PDGFRL Products)

Synonyms: zgc:56104 antibody, zgc:77677 antibody, MGC82397 antibody, PDGFRL antibody, pdgrl antibody, prlts antibody, MGC107901 antibody, PDGRL antibody, PRLTS antibody, 1110039P19Rik antibody, AV013190 antibody, platelet-derived growth factor receptor-like antibody, platelet derived growth factor receptor like L homeolog antibody, platelet derived growth factor receptor like antibody, pdgfrl antibody, pdgfrl.L antibody, PDGFRL antibody, Pdgfrl antibody

Background: This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
Alias Symbols: PDGRL, PRLTS
Protein Size: 375

Molecular Weight: 38 kDa

Gene ID: 5157

NCBI Accession: NM_006207, NP_006198

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling