IST1 antibody (N-Term)

Catalog No. ABIN2790798

Product Details anti-IST1 Antibody

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IST1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: INRLKLLEKK KTELAQKARK EIADYLAAGK DERARIRVEH IIREDYLVEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against IST1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IST1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 360 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IST1

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Alternative Name: IST1 (IST1 Products)

Synonyms: 2400003C14Rik antibody, AW536298 antibody, mKIAA0174 antibody, RGD1307799 antibody, OLC1 antibody, fb16b04 antibody, wu:fb16b04 antibody, wu:fi89e07 antibody, zgc:55671 antibody, ist1 antibody, kiaa0174 antibody, pm28 antibody, increased sodium tolerance 1 homolog (yeast) antibody, IST1, ESCRT-III associated factor antibody, increased sodium tolerance 1 homolog S homeolog antibody, Ist1 antibody, IST1 antibody, ist1 antibody, ist1.S antibody

Background: IST1 is proposed to be involved in specific functions of the ESCRT machinery. It is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvment in the MVB pathway is not established. IST1 is involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
Alias Symbols: IST1, MGC117220
Protein Interaction Partner: APEH, UBQLN1, CAPN7, UBC, BTF3L4, TIMM13, VCAM1, ITGA4, FN1, ERGIC1, MAT1A, HSPA5, ATP6V1B1, ATXN1, SPAST, FZR1, ANAPC2, CDC20, CHMP1B,
Protein Size: 360

Molecular Weight: 40 kDa

Gene ID: 9798

NCBI Accession: NM_014761, NP_055576

Pathways: Regulation of Cell Size