GPR37 antibody (C-Term)
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- Target See all GPR37 Antibodies
- GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
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Binding Specificity
- AA 217-246, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GPR37 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- Rabbit Anti-Human Pael-R (GPR37) (C-term) Antibody
- Immunogen
- This Pael-R (GPR37) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human Pael-R (GPR37).
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GPR37 Primary Antibody
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- Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-Pael-R (GPR37) Antibody (C-term) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))
- Alternative Name
- Pael-R (GPR37 Products)
- Synonyms
- ACCA antibody, EDNRBL antibody, PAELR antibody, hET(B)R-LP antibody, AI848630 antibody, Pael-R antibody, Ednrbl antibody, G protein-coupled receptor 3 antibody, G protein-coupled receptor 37 antibody, GPR3 antibody, GPR37 antibody, Gpr37 antibody
- Background
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Target Description: Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known, however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons, coexpression of Parkin degrades Pael-R and suppresses its toxicity.
Gene Symbol: GPR37
- Molecular Weight
- 67114 Da
- Gene ID
- 2861
- UniProt
- O15354
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