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Ataxin 3 antibody

KO Validated ATXN3 Reactivity: Human WB, IF, IP, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854322
  • Target See all Ataxin 3 (ATXN3) Antibodies
    Ataxin 3 (ATXN3)
    Reactivity
    • 63
    • 32
    • 31
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 60
    • 2
    • 1
    Rabbit
    Clonality
    • 62
    • 1
    Polyclonal
    Conjugate
    • 26
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ataxin 3 antibody is un-conjugated
    Application
    • 48
    • 25
    • 23
    • 13
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to Ataxin 3 (ataxin-3)
    Ataxin 3 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Ataxin 3. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ATXN3 Primary Antibody
  • Application Notes
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: SK-N-SH , SK-N-AS , human Ataxin3-transfected 293T , 293T , A431 , HeLa , HepG2

    Validation: KO/KD, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.55 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Ataxin 3 (ATXN3)
    Alternative Name
    ataxin 3 (ATXN3 Products)
    Synonyms
    Mjd antibody, zgc:56323 antibody, ATXN3 antibody, at3 antibody, jos antibody, mjd antibody, atx3 antibody, mjd1 antibody, sca3 antibody, ataxin-3 antibody, MJD1 antibody, MGC83584 antibody, AT3 antibody, ATX3 antibody, JOS antibody, MJD antibody, SCA3 antibody, 2210008M02Rik antibody, AI463012 antibody, AI647473 antibody, Sca3 antibody, Rsca3 antibody, ataxin 3 antibody, ataxin 3 L homeolog antibody, ataxin-3 antibody, atxn3 antibody, ATXN3 antibody, atxn3.L antibody, MICPUN_104046 antibody, MICPUCDRAFT_46658 antibody, Atxn3 antibody
    Background
    Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Cellular Localization: Nucleus matrix
    Molecular Weight
    42 kDa
    Gene ID
    4287
    UniProt
    P54252
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