MTMR2 antibody (C-Term)

Catalog No. ABIN2854399

Product Details anti-MTMR2 Antibody

Target: MTMR2 (Myotubularin Related Protein 2 (MTMR2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to MTMR2 (myotubularin related protein 2)
MTMR2 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human MTMR2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MTMR2

Target: MTMR2 (Myotubularin Related Protein 2 (MTMR2))

Alternative Name: myotubularin related protein 2 (MTMR2 Products)

Synonyms: MTMR2 antibody, DKFZp459I198 antibody, CMT4B antibody, CMT4B1 antibody, 6030445P13Rik antibody, zgc:153915 antibody, myotubularin related protein 2 antibody, MTMR2 antibody, Mtmr2 antibody, mtmr2 antibody

Background: This gene is a member of the myotubularin family. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene.

Cellular Localization: Cytoplasm , Membrane, Peripheral membrane protein

Molecular Weight: 73 kDa

Gene ID: 8898

UniProt: Q13614

Pathways: Inositol Metabolic Process, Synaptic Membrane