SLC4A8 antibody (N-Term)

Catalog No. ABIN2855611

Product Details anti-SLC4A8 Antibody

Target: SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC4A8 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Mouse (93 %), Rat (92 %)

Characteristics: Rabbit Polyclonal antibody to SLC4A8 (solute carrier family 4, sodium bicarbonate cotransporter, member 8)
SLC4A8 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human SLC4A8. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: IMR32 , U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.99 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SLC4A8

Target: SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))

Alternative Name: SLC4A8 (SLC4A8 Products)

Synonyms: SLC4A8 antibody, AW493845 antibody, C230026C11 antibody, NDCBE antibody, kNBC-3 antibody, NBC3 antibody, KNBC3 antibody, solute carrier family 4, sodium bicarbonate cotransporter, member 8 S homeolog antibody, solute carrier family 4 member 8 antibody, solute carrier family 4, sodium bicarbonate cotransporter, member 8 antibody, solute carrier family 4 (anion exchanger), member 8 antibody, slc4a8.S antibody, SLC4A8 antibody, slc4a8 antibody, Slc4a8 antibody

Background: Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Cellular Localization: Membrane, Multi-pass membrane protein

Molecular Weight: 123 kDa

Gene ID: 9498