MPI antibody

Catalog No. ABIN2855680

Product Details anti-MPI Antibody

Target: MPI (Mannose Phosphate Isomerase (MPI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Characteristics: Rabbit Polyclonal antibody to MPI (mannose phosphate isomerase)
MPI antibody

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human MPI. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , PC-12 , Rat2 , HeLa

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MPI

Target: MPI (Mannose Phosphate Isomerase (MPI))

Alternative Name: mannose phosphate isomerase (MPI Products)

Synonyms: CDG1B antibody, PMI antibody, PMI1 antibody, 1110002E17Rik antibody, AI315153 antibody, Mpi-1 antibody, Mpi1 antibody, im:7140016 antibody, zgc:110773 antibody, cdg1b antibody, pmi antibody, pmi1 antibody, CaO19.1390 antibody, mannose phosphate isomerase antibody, mannose phosphate isomerase S homeolog antibody, mannose phosphate isomerase (mapped) antibody, mannose-6-phosphate isomerase antibody, MPI antibody, Mpi antibody, mpi antibody, mpi.S antibody, PMI1 antibody

Background: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.

Cellular Localization: Cytoplasm

Molecular Weight: 47 kDa

Gene ID: 4351

UniProt: P34949