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CD3 antibody (CD3) (APC-Cy7)

Details for Product anti-CD3 Antibody No. ABIN288844, Supplier: Log in to see
Antigen
  • CD3
Reactivity
Human
742
198
72
42
32
25
19
17
13
10
10
7
7
6
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
Host
Mouse
819
138
59
47
Clonality (Clone)
Monoclonal ()
Conjugate
This CD3 antibody is conjugated to APC-Cy7
155
106
88
67
22
21
19
16
16
16
15
15
14
11
10
8
7
7
6
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
828
200
169
106
104
104
103
76
56
43
19
12
11
10
10
9
7
4
4
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
Supplier
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Immunogen CD3 antibody (Allophycocyanin-CY7) was raised in mouse using the epsilon chain of CD3/T-cell antigen receptor complex as the immunogen.
Clone UCHT1
Isotype IgG1
Alternative Name CD3 (CD3 Antibody Abstract)
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Optimal conditions should be determined byt he investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer Supplied as a liquid in PBS, with NaN3 added as preservative.
Preservative Sodium azide
Precaution of Use This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Product is photosensitive and should be protected from light.
Dilute only prior to immediate use.
Storage 4 °C
Background publications Rieux-Laucat, Hivroz, Lim et al.: "Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency." in: The New England journal of medicine, Vol. 354, Issue 18, pp. 1913-21, 2006 (PubMed).

Lin, Liu, Chen et al.: "CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features." in: Blood, Vol. 106, Issue 10, pp. 3567-74, 2005 (PubMed).

Demedts, Brusselle, Vermaelen et al.: "Identification and characterization of human pulmonary dendritic cells." in: American journal of respiratory cell and molecular biology, Vol. 32, Issue 3, pp. 177-84, 2005 (PubMed).

Arnett, Harrison, Wiley: "Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 46, pp. 16268-73, 2004 (PubMed).

Torres, Alcover, Zapata et al.: "TCR dynamics in human mature T lymphocytes lacking CD3 gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 5947-55, 2003 (PubMed).

le Gouvello, Manceau, Sobel: "Serine 16 of stathmin as a cytosolic target for Ca2+/calmodulin-dependent kinase II after CD2 triggering of human T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 3, pp. 1113-22, 1998 (PubMed).