ADAMTS4 antibody (Internal Region)

Catalog No. ABIN290074

This Rabbit Polyclonal antibody specifically detects ADAMTS4 in IHC and IHC (p). It exhibits reactivity toward Human, Horse, Dog, Monkey and Bat.

Quick Overview for ADAMTS4 antibody (Internal Region) (ABIN290074)

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Reactivity: Human, Horse, Dog, Monkey, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADAMTS4 Antibody

Binding Specificity: Internal Region

Specificity: Human ADAMTS4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADAMTS8 (53 % ).

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Marmoset, Dog, Bat, Panda, Horse (100%) Elephant, Pig (95%) Mouse (89%) Bovine (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 19 amino acid peptide from internal region of human ADAMTS4. Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Marmoset, Dog, Bat, Panda, Horse (100%), Elephant, Pig (95%), Mouse (89%), Bovine (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.6 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.6 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADAMTS4

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Alternative Name: ADAMTS4

Background: Name/Gene ID: ADAMTS4
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAMTS4, ADAMTS-2, ADAMTS-4, ADAM-TS 4, ADAM-TS4, ADMP-1, Aggrecanase-1, KIAA0688

Gene ID: 9507