IKBKB antibody (AA 310-376)

Catalog No. ABIN297183

The Chicken Polyclonal anti-IKBKB antibody (ABIN297183) specifically detects IKBKB in WB, IHC and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IKBKB antibody (AA 310-376) (ABIN297183)

Target: IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This IKBKB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IKBKB Antibody

Binding Specificity: AA 310-376

Specificity: Amino acids 310-376 of human IKBKB

Purification: Immunoaffinity purified

Immunogen: Recombinant human IKBKB / IKK Beta.

Type of Immunogen: Recombinant protein

Isotype: IgY

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS. No preservative added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IKBKB

Target: IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

Alternative Name: IKBKB / IKK2 / IKK Beta

Background: Name/Gene ID: IKBKB
Subfamily: IKAPPAB
Family: Protein Kinase

Synonyms: IKBKB, Ikk 2, IKK-B, IKK2, IKKbeta, NFKBIKB, I-kappa-B kinase 2, IKKB, I-kappa-B-kinase beta, Ikb kinase-beta, IKK Beta, IKK-beta

Gene ID: 3551

UniProt: O14920

Pathways: NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins