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Details for Product No. ABIN302239

Intercellular Adhesion Molecule 1 (ICAM1) antibody (APC)

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Antigen
Synonyms BB2, CD54, P3.58, Icam-1, Ly-47, MALA-2, ICAM1, ICAM-1, ICAM
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 4 references available
Catalog no. ABIN302239
Quantity 100 tests
Price
401.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Raji cells and spleen cells fused with NS1 cells
Clone 1H4
Isotype IgG2b
Characteristics Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
Purification Size-exclusion chromatography
Alternative Name CD54 / ICAM1
Background CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is atransmembrane molecule with 7 potential N-glycosylated sites, expressed on restingmonocytes and endothelial cells and can be upregulated on many other cells, e. g. withlymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also onkeratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion bybinding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54with LFA-1 enhances antigen-specific T-cell activation.
UniProt P05362
Application Notes Flow Cytometry analysis of human blood cells using 10 l reagent / 100 l of whole bloodor 10e6 cells in a suspension. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
Preservative Sodium azide
Storage 4 °C
Storage Comment Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Ockenhouse, Betageri, Springer et al.: "Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus." in: Cell, Vol. 68, Issue 1, pp. 63-9, 1992 (PubMed).

Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, 1990 (PubMed).

Boyd, Dunn, Fecondo et al.: "Regulation of expression of a human intercellular adhesion molecule (ICAM-1) during lymphohematopoietic differentiation." in: Blood, Vol. 73, Issue 7, pp. 1896-903, 1989 (PubMed).

Boyd, Wawryk, Burns et al.: "Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell-cell contact-mediated immune mechanisms." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 9, pp. 3095-9, 1988 (PubMed).

Alternatives for antigen "Intercellular Adhesion Molecule 1 (ICAM1)", type "Antibodies"
Hosts (323), (219), (70), (5), (5), (3)
Reactivities (497), (144), (95), (47), (34), (18), (17), (3), (1), (1)
Applications (371), (227), (141), (123), (121), (79), (74), (66), (43), (41), (41), (31), (13), (7), (6), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Conjugates (68), (55), (41), (10), (10), (9), (9), (8), (8), (8), (8), (8), (8), (7), (4), (4), (4), (4), (2), (2), (1), (1), (1)
Epitopes (31), (11), (6), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
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