Intercellular Adhesion Molecule 1 (ICAM1) antibody (PE)

Details for Product No. ABIN302244
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Antigen
Synonyms BB2, CD54, P3.58, Icam-1, Ly-47, MALA-2, ICAM, ICAM-1, ICAM1
Reactivity
Human
(467), (124), (69), (8), (2), (1)
Host
Mouse
(306), (215), (71), (6), (4), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
PE
(56), (54), (49), (9), (7), (7), (6), (5), (5), (5), (5), (5), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(335), (234), (136), (108), (101), (99), (64), (50), (39), (38), (31), (16), (16), (12), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1)
Pubmed 5 references available
Quantity 100 tests
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Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN302244
412.50 $
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Immunogen Raji cells and spleen cells fused with NS1 cells
Clone 1H4
Isotype IgG2b
Cross-Reactivity (Details) Species reactivity (tested):Human.
Characteristics Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
Purification Size-Exclusion Chromatography
Alternative Name CD54 / ICAM1
Background CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
UniProt P05362
Application Notes Flow Cytometry: Use 20 μL to label 10^6 cells or 100 μL whole blood or blood or 10^6 cellsin a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Intercellular Adhesion Molecule 1 (ICAM1) antibody (PE) anti-Intercellular Adhesion Molecule 1 (ICAM1) antibody (PE)
Background publications Ockenhouse, Betageri, Springer et al.: "Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus." in: Cell, Vol. 68, Issue 1, pp. 63-9, 1992 (PubMed).

Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, 1990 (PubMed).

Boyd, Dunn, Fecondo et al.: "Regulation of expression of a human intercellular adhesion molecule (ICAM-1) during lymphohematopoietic differentiation." in: Blood, Vol. 73, Issue 7, pp. 1896-903, 1989 (PubMed).

Boyd, Wawryk, Burns et al.: "Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell-cell contact-mediated immune mechanisms." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 9, pp. 3095-9, 1988 (PubMed).

Williams, Chaudhry, Goodfellow et al.: "Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites." in: The Journal of general virology, Vol. 85, Issue Pt 3, pp. 731-8, 2004 (PubMed).

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