GPRC6A antibody (Extracellular Domain, N-Term)

Catalog No. ABIN302376

The Rabbit Polyclonal anti-GPRC6A antibody (ABIN302376) specifically detects GPRC6A in IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GPRC6A antibody (Extracellular Domain, N-Term) (ABIN302376)

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRC6A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GPRC6A Antibody

Binding Specificity: Extracellular Domain, N-Term

Specificity: Reacts with G Protein-Coupled Receptor GPRC6A (family: GPCR, subfamily: Amino Acid Receptor)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: GPRC6A antibody was raised against synthetic 18 amino acid peptide from N-terminal extracellular domain of Human GPRC6A.

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for GPRC6A

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Background: GPRC6A has been shown to bind to L-alpha-amino acids. Recently GPRC6A has been suggested to be a calcium-sensing receptor (Pi et al. 2005). Ligand: L-alpha-amino acids, including L-Arg, L-Lys and L-ornithineSynonyms: G-protein coupled receptor family C group 6 member A

Gene ID: 222545

NCBI Accession: NP_683766

UniProt: Q5T6X5