DPP4 antibody (N-Term)

Catalog No. ABIN302556

The Rabbit Polyclonal anti-DPP4 antibody (ABIN302556) specifically detects DPP4 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for DPP4 antibody (N-Term) (ABIN302556)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DPP4 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects Human Dipeptidylpeptidase 4/DPP4 (CD26) at N-terminal domain. BLAST analysis of the peptide immunogen showed no homology with other Human proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic 15 amino acid peptide corresponding to the N-terminal domain of Human CD26

Application Details

Application Notes: Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26 / DPP4

Background: CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein] is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.Synonyms: ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103

Gene ID: 1803

NCBI Accession: NP_001926

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity