Ectodysplasin A2 Receptor antibody

Catalog No. ABIN303257

The Rabbit Polyclonal anti-Ectodysplasin A2 Receptor antibody is suitable to detect Ectodysplasin A2 Receptor in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Ectodysplasin A2 Receptor antibody (ABIN303257)

Target: Ectodysplasin A2 Receptor (EDA2R)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A2 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Ectodysplasin A2 Receptor Antibody

Specificity: This antibody reacts to Human EDA2R, antibody does not detect mouse EDA2R.

Purification: Purified

Immunogen: Recombinant human EDA2R

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Ectodysplasin A2 Receptor

Target: Ectodysplasin A2 Receptor (EDA2R)

Alternative Name: EDA2R / TNFRSF27

Background: EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR

Gene ID: 60401

NCBI Accession: NP_001186616

UniProt: Q9HAV5