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Plasminogen Activator, Urokinase (PLAU) antibody

Antigen

Plasminogen Activator, Urokinase (PLAU)

Synonyms ATF, UPA, URK, u-PA, uPA, UPAM, MGC124931, PLAU, MGC139972, LOC100008633, plau, DKFZp469F0732
Clonality Monoclonal (PGM2001)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
Catalog no. ABIN303620
Quantity 1 ml (0.2 mg)
Price 234.00 $   Plus shipping costs $35.00
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Availability Ships within 3 to 5 Business Days

Additional Information

Alternative name Urokinase
Immunogen Urokinase
Format Lyophilized
Isotype IgG1  (Matching secondary antibodies)
Clone PGM2001
Description Mouse anti-human urokinase monoclonal antibody, Unconjugated, Clone PGM2001
Specificity Binds to human high molecular weight single-chain urokinase type plasminogen activator (HMW-scuPA, 54 kDa), to high molecular weight two-chain urokinase type plasminogen activator (HMW-tcuPA, 52 kDa) and to low molecular weight single-chain urokinase type plasminogen activator (LMW-scuPA, 33kDa) with high affinity (Kd = 0.1 nM) and does inhibit the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is not inhibited. Highly specific for urokinase, no cross-reactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, and thrombin). Human plasma or plasma proteins do not interfere with its binding to urokinase.

Application Details

Application Notes Use 1 ml sterile pure water
Purification Precipitation by PEG-6000 and DEAE-cellulose chromatography (gradient)
Buffer Lyophilised from solution containing 0.2 mg antibody, 1% mannitol, 0.15 M sodium chloride, 0.01 M sodium phosphate. Azide-free
Storage -20°C
Research Area Cancer, Alzheimer's Disease, Enzymes, Metabolism
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Plasminogen Activator, Urokinase (PLAU)", type "Antibodies"
Hosts Rabbit (39), Sheep (33), Mouse (22), Goat (11), Rat (1)
Reactivities Human (55), Mouse (Murine) (31), Rat (Rattus) (15), Dog (Canine) (9), Rabbit (7)
Applications Western Blotting (WB) (79), Enzyme Immunoassay (EIA) (38), ELISA (Detection) (37), ELISA (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Radioimmunoassay (RIA) (11), Immunohistochemistry (IHC) (6), Immunoprecipitation (IP) (4), ELISA (Capture) (3), Flow Cytometry (FACS) (2), Functional Studies (Func) (2), Immunocytochemistry (ICC) (2)
Conjugates Biotin (7), FITC (6), HRP (6)
Epitopes C-Term (4), N-Term (2)