ST5 antibody (Middle Region)

Catalog No. ABIN3042548

Product Details anti-ST5 Antibody

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Binding Specificity: AA 571-586, Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Suppression of tumorigenicity 5 protein(ST5) detection. Tested with WB in Human,Mouse,Rat.

Sequence: KRHSHDDMLL LAQLSL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Suppression of tumorigenicity 5 protein(ST5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: suppression of tumorigenicity 5
Protein Name: Suppression of tumorigenicity 5 protein

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ST5(571-586aa KRHSHDDMLLLAQLSL), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: ST5 (ST5 Products)

Synonyms: zgc:91902 antibody, wu:fc11b09 antibody, si:ch211-208c6.1 antibody, ST5 antibody, DKFZp459D1230 antibody, hts1 antibody, p126 antibody, dennd2b antibody, DENND2B antibody, HTS1 antibody, 2010004M01Rik antibody, 2610305K15Rik antibody, suppression of tumorigenicity 5 antibody, st5 antibody, ST5 antibody, St5 antibody

Background: Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. This gene is mapped to 11p15.4. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Synonyms: DENN domain containing protein 2B antibody|DENN domain-containing protein 2B antibody|DENN/MADD domain containing 2B antibody|DENND2B antibody|HeLa tumor suppression 1 antibody|HTS1 antibody|p126 antibody|ST 5 antibody|ST5 antibody|Suppression of tumorigenicity 5 antibody|Suppression of tumorigenicity 5 protein antibody

UniProt: P78524