Ectodysplasin A antibody (Middle Region)

Catalog No. ABIN3042668

Product Details anti-Ectodysplasin A Antibody

Target: Ectodysplasin A (EDA)

Binding Specificity: AA 254-269, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ectodysplasin-A(EDA) detection. Tested with WB in Human,Mouse,Rat.

Sequence: HLQGQGSAIQ VKNDLS

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Ectodysplasin-A(EDA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ectodysplasin A
Protein Name: Ectodysplasin-A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human EDA(254-269aa HLQGQGSAIQVKNDLS), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

References for anti-Ectodysplasin A antibody (ABIN3042668)

Ning, Chen, Li, Wu, Wu, Li, Feng: "X-irradiation for inhibiting glial scar formation in injured spinal cord." in: Neural regeneration research, Vol. 8, Issue 17, pp. 1582-9, (2014) (PubMed).

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA (EDA Products)

Synonyms: ECTD1 antibody, ED1 antibody, ED1-A1 antibody, ED1-A2 antibody, EDA-A1 antibody, EDA-A2 antibody, EDA1 antibody, EDA2 antibody, HED antibody, HED1 antibody, ODT1 antibody, STHAGX1 antibody, XHED antibody, XLHED antibody, si:ch73-223d24.5 antibody, Ed1 antibody, Eda-A1 antibody, Eda-A2 antibody, Ta antibody, tabby antibody, RGD1563178 antibody, ectodysplasin A antibody, ectodysplasin-A antibody, EDA antibody, eda antibody, Eda antibody

Background: Anhidrotic ectodermal dysplasia(EDA) is an X-linked recessive disorder which affects ectodermal structures. Ectodysplasin-A, the protein encoded by the EDA gene, is a member of the tumor necrosis factor ligand superfamily that forms a collagen triple helix, suggesting functions in signal transduction and cell adhesion. Wnt signaling does control EDA gene expression, but ectodysplasin-A does not feedback on the Wnt pathway.

Synonyms: Ectodermal dysplasia 1, anhidrotic antibody|Ectodermal dysplasia protein antibody|Ectodermal dysplasia, anhidrotic(hypohydrotic) antibody|Ectodysplasin A antibody|Ectodysplasin A, membrane form antibody|Ectodysplasin A, secreted form antibody|ECTODYSPLASIN A1 ISOFORM antibody|ECTODYSPLASIN A2 ISOFORM antibody|ECTODYSPLASIN antibody|Ectodysplasin-A antibody|ED1 A1 antibody|ED1 A2 antibody|ED1 antibody|ED1 GENE antibody|Eda A1 antibody|Eda A2 antibody|eda antibody|EDA protein antibody|EDA protein homolog antibody|EDA_HUMAN antibody|EDA1 antibody|EDA1 GENE antibody|EDA2 antibody|HED antibody|ODT1 antibody|Oligodontia 1 antibody|secreted form antibody|STHAGX1 antibody|Ta antibody|Tabby antibody|Tabby protein antibody|X linked anhidroitic ectodermal dysplasia protein antibody|XHED antibody|XLHED antibody

UniProt: Q92838

Pathways: Tube Formation