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CRY2 antibody (N-Term)

CRY2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042760
  • Target See all CRY2 Antibodies
    CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))
    Binding Specificity
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-200, N-Term
    Reactivity
    • 31
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 6
    Rabbit
    Clonality
    • 29
    • 4
    Polyclonal
    Conjugate
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRY2 antibody is un-conjugated
    Application
    • 26
    • 11
    • 10
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Cryptochrome-2(CRY2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    RFQAIISRME LPKKPVGLVT SQQMESCRAE
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Cryptochrome-2(CRY2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: cryptochrome circadian clock 2
    Protein Name: Cryptochrome-2
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human CRY2 (171-200aa RFQAIISRMELPKKPVGLVTSQQMESCRAE), different from the related mouse and rat sequences by five amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CRY2 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))
    Alternative Name
    CRY2 (CRY2 Products)
    Synonyms
    Cry2 antibody, Cry antibody, GB10211 antibody, CRY2 antibody, AT-PHH1 antibody, ATCRY2 antibody, CRYPTOCHROME 2 APOPROTEIN antibody, F19P19.14 antibody, F19P19_14 antibody, FHA antibody, PHH1 antibody, cryptochrome 2 antibody, HCRY2 antibody, PHLL2 antibody, AV006279 antibody, D130054K12Rik antibody, gCry2 antibody, cryptochrome circadian regulator 2 antibody, cryptochrome 2 antibody, cryptochrome Cry2 antibody, cryptochrome circadian clock 2 antibody, cryptochrome 2 (photolyase-like) antibody, CRY2 antibody, Cry2 antibody, cry2 antibody, LOC100502533 antibody
    Background
    This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. And it is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

    Synonyms: cry2 antibody|CRY2_HUMAN antibody|cryptochrome 2 (photolyase like) antibody|Cryptochrome 2 antibody|Cryptochrome-2 antibody|FLJ10332 antibody|growth inhibiting protein 37 antibody|HCRY2 antibody|KIAA0658 antibody|PHLL2 antibody|Photolyase like antibody
    Gene ID
    1408
    Pathways
    Response to Water Deprivation, Protein targeting to Nucleus
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