ATP1A1 antibody (N-Term)

Catalog No. ABIN3043505

Product Details anti-ATP1A1 Antibody

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Binding Specificity: AA 7-34, N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Sodium/potassium-transporting ATPase subunit alpha-1(ATP1A1) detection. Tested with WB in Human,Rat.

Sequence: RDKYEPAAVS EQGDKKGKKG KKDRDMDE

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Sodium/potassium-transporting ATPase subunit alpha-1(ATP1A1) detection. Tested with WB in Human,Rat.
Gene Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Protein Name: Sodium/potassium-transporting ATPase subunit alpha-1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ATP1A1 (7-34aa RDKYEPAAVSEQGDKKGKKGKKDRDMDE), different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: ATP1A1 (ATP1A1 Products)

Synonyms: Atpa-1 antibody, BC010319 antibody, Nkaa1b antibody, K-ATPase antibody, Na+K+ATPase antibody, atp1a1 antibody, atp1a1a.1 antibody, atp1a1l1 antibody, atp[a]1B1 antibody, cb70 antibody, wu:fa03c03 antibody, wu:fb92h10 antibody, atp1a1l5 antibody, atp[a]1B2 antibody, cb707 antibody, wu:fj34g01 antibody, zgc:92351 antibody, ATPase Na+/K+ transporting subunit alpha 1 antibody, ATPase, Na+/K+ transporting, alpha 1 polypeptide antibody, ATPase Na+/K+ transporting subunit alpha 1 L homeolog antibody, ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1 antibody, ATPase, Na+/K+ transporting, alpha 1b polypeptide antibody, ATP1A1 antibody, Atp1a1 antibody, atp1a1.L antibody, atp1a1a.1 antibody, atp1a1b antibody

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: A1A1 antibody|AT1A1 antibody|AT1A1_HUMAN antibody|ATP1A1 antibody|Atpa-1 antibody|ATPase Na+/K+ transporting alpha 1 polypeptide antibody|BC010319 antibody|EC 3.6.3.9 antibody| MGC3285 antibody|MGC38419 antibody|MGC51750 antibody|Na K ATPase alpha A catalytic polypeptide antibody|Na K ATPase catalytic subunit alpha A protein antibody|Na(+)/K(+) ATPase 1 antibody|Na(+)/K(+) ATPase alpha-1 subunit antibody|Na+/K+ ATPase alpha 1 subunit antibody|Na+/K+ ATPase 1 antibody|Nkaa1b antibody|Sodium potassium ATPase alpha 1 polypeptide antibody|Sodium pump 1 antibody|Sodium pump subunit alpha-1 antibody|sodium-potassium ATPase catalytic subunit alpha-1 antibody|Sodium/potassium transporting ATPase alpha 1 chain antibody|Sodium/potassium-transporting ATPase subunit alpha-1 antibody

Gene ID: 476

UniProt: P05023

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process