SLC19A1 antibody (Middle Region)

Catalog No. ABIN3043543

Product Details anti-SLC19A1 Antibody

Target: SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))

Binding Specificity: AA 202-231, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC19A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Folate transporter 1(SLC19A1) detection. Tested with WB in Human.

Sequence: FLKRPKRSLF FNRDDRGRCE TSASELERMN

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Folate transporter 1(SLC19A1) detection. Tested with WB in Human.
Gene Name: solute carrier family 19 (folate transporter), member 1
Protein Name: Folate transporter 1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SLC19A1 (202-231aa FLKRPKRSLFFNRDDRGRCETSASELERMN).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SLC19A1

Target: SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))

Alternative Name: SLC19A1 (SLC19A1 Products)

Synonyms: A1 antibody, MHCBFB antibody, PO-GA antibody, RECC1 antibody, RFC antibody, RFC140 antibody, CHMD antibody, FOLT antibody, IFC1 antibody, REFC antibody, RFC1 antibody, LOC100226745 antibody, AI323572 antibody, RFC-1 antibody, MTX1 antibody, XRFC antibody, chmd antibody, folt antibody, ifc1 antibody, refc antibody, rfc1 antibody, slc19a1 antibody, replication factor C subunit 1 antibody, solute carrier family 19 member 1 antibody, folate transporter 1 antibody, solute carrier family 19 (folate transporter), member 1 antibody, solute carrier family 19 (folate transporter), member 1 L homeolog antibody, RFC1 antibody, SLC19A1 antibody, LOC100226745 antibody, Slc19a1 antibody, slc19a1.L antibody

Background: Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate.

Synonyms: CHMD antibody|FLOT 1 antibody|FLOT1 antibody|Folate transporter 1 antibody|FOLT antibody| IFC 1 antibody|IFC-1 antibody|IFC1 antibody|Intestinal folate carrier 1 antibody|Intestinal folate carrier antibody|OTTHUMP00000115459 antibody|OTTHUMP00000115460 antibody|Placental folate transporter antibody|Reduced folate carrier antibody|Reduced folate carrier protein antibody|REFC antibody|RFC 1 antibody|RFC antibody|RFC1 antibody|S19A1_HUMAN antibody| SLC19A1 antibody|Solute carrier family 19 member 1 antibody

Gene ID: 6573

UniProt: P41440

Pathways: Dicarboxylic Acid Transport