Caspase 7 antibody

Catalog No. ABIN306554

The Rabbit Polyclonal anti-Caspase 7 antibody is suitable to detect Caspase 7 in samples from Human. It has been validated for WB.

Quick Overview for Caspase 7 antibody (ABIN306554)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 7 Antibody

Purpose: Rabbit anti Human Caspase-7

Characteristics: Caspase-7 along with caspase 3 and 6 form the group of effector caspases that are responsible for the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others. Caspase-7 occurs in three varient forms.Exalphas rabbit anti-human caspase-7 antibody reacts with the zymogen and with the 20-23 kDa subunit of caspase-7. Cells should be pretreated with 200 ng/mL of deoxyrubicin for one half hour. Exalphas caspase-7 antibody was generated by immunizing rabbits with the aa 186-198 of human caspase-7.

Purification: Ammonium Sulfate Precipitation

Immunogen: Rabbits with the aa 186-198 of human caspase-7

Isotype: IgG

Application Details

Application Notes: Applications: western blot, use at 2-10 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: Caspase-7 (ICE, LAP3, Mch3, CHM-1)

Background: Cysteine-requiring Aspartate Protease-7, Apoptotic protease Mch-3, ICE-like apoptotic protease 3

UniProt: P55210

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity