TR4 antibody (full length)

Catalog No. ABIN306727

This Sheep Polyclonal antibody specifically detects TR4 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for TR4 antibody (full length) (ABIN306727)

Target: TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This TR4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-TR4 Antibody

Binding Specificity: full length

Purpose: Sheep anti Human TAK1

Cross-Reactivity: Human

Characteristics: C-TAK1 (Cdc25C associated protein kinase) is a ubiquitously expressed protein kinase found in human tissues and cell lines and can phosphorylate Cdc25C on serine 216 in vitro. C-TAK1 is distinct from the DNA damage checkpoint kinase Chk1 and may regulate interactions between Cdc25C and 14-3-3 in vivo by phosphorylating Cdc25C at serine 216.

Purification: Ammonium Sulfate Precipitation

Immunogen: Recombinant, full-length His-tagged human C-TAK1 produced in E. Coli.

Isotype: IgG

Application Details

Application Notes: Antibody detects c-tak1 by Western blot analysis at 1 to 5 μg/mL. Detects c-tak1 in RKO and HCT116 cell lysates. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for TR4

Target: TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Alternative Name: TAK1

Background: Mark3, Sheep anti-Cdc25c associated protein kinase-1, human

UniProt: P27448

Pathways: TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades