UGCG antibody
Quick Overview for UGCG antibody (ABIN306948)
Target
See all UGCG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Rabbit anti Human Ceramide Glycosyltransferase
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Cross-Reactivity
- Human
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Characteristics
- Ceramide Glycosyltransferase may serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes, UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis, first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
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Purification
- Ammonium Sulfate Precipitation
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Application Notes
- Antibody can be used for Western blotting (5-10 μg/mL) and ELISA. Other applications not yet tested. Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))
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Alternative Name
- Ceramide Glycosyltransferase
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Background
- Glucosylceramide synthase, GCS, UDP glucose N-acylsphingosine D glucosyltransferase, GLCT-1, UDP glucose ceramide glucosyltransferase
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UniProt
- Q16739
Target
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