UGCG antibody (AA 21-120)

Catalog No. ABIN672096

Product Details anti-UGCG Antibody

Target: UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

Binding Specificity: AA 21-120

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-UGCG antibody (ABIN672096)

Chen, Yin, Cheng, Ding, Gao, Sun, Zhao, Wang, Bao, Xia, Gao, Wang: "Effect of D, L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol and tetrandrine on the reversion of multidrug resistance in K562/A02 cells." in: Hematology (Amsterdam, Netherlands), Vol. 16, Issue 1, pp. 24-30, (2011) (PubMed).

Target Details for UGCG

Target: UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

Alternative Name: Ceramide glucosyltransferase (UGCG Products)

Background:

Synonyms: GCS, GLCT1, Ceramide glucosyltransferase, GLCT-1, Glucosylceramide synthase, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, UGCG

Background: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".

Gene ID: 7357

UniProt: Q16739