SAMD8 antibody

Catalog No. ABIN306952

Product Details anti-SAMD8 Antibody

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMD8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Characteristics: Sphingomyelin synthase-related 1, Sterile alpha motif domain containing 8, SAMD8,Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.

Purification: Ammonium Sulfate Precipitation

Immunogen: Full-length recombinant sphingomyelin synthase r fusion protein

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for SAMD8

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Alternative Name: Sphingomyelin synthase-related protein 1 (SAMD8 Products)

Synonyms: CG32380 antibody, CG8572 antibody, CG8576 antibody, Css3beta antibody, Dmel\\CG32380 antibody, dSMSr antibody, dmSMSr antibody, SMSr antibody, 1110053F04Rik antibody, 1700010P07Rik antibody, CG32380 gene product from transcript CG32380-RA antibody, sterile alpha motif domain containing 8 antibody, SMSr antibody, SAMD8 antibody, samd8 antibody, Samd8 antibody

UniProt: Q96LT4