CD130/gp130 antibody (PE)

Catalog No. ABIN307232

The Mouse Monoclonal anti-CD130/gp130 antibody is suitable to detect CD130/gp130 in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for CD130/gp130 antibody (PE) (ABIN307232)

Target: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD130/gp130 antibody is conjugated to PE

Application: ELISA, Flow Cytometry (FACS)

Product Details anti-CD130/gp130 Antibody (PE)

Specificity: Recognizes soluble and membrane bound human gp130 receptor. This antibody has been reported to block the activity of IL-6.

Purification: Ion exchange chromatography

Immunogen: Natural soluble gp130 receptor.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo

Usage: Suitable for use in ELISA and Flow Cytometry. Flow Cytometry: 0.2 μg/1 x10⁶. Use 20 μL to label 1 x10⁶ in 100 μL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD130/gp130

Target: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Alternative Name: CD130 / IL6ST / gp130

Background: Name/Gene ID: IL6ST
Family: Interleukin

Synonyms: IL6ST, CD130, CD130 antigen, IL-6R subunit beta, IL-6 receptor subunit beta, Membrane glycoprotein gp130, Membrane glycoprotein 130, IL-6RB, CDW130, gp130, IL-6R-beta

Gene ID: 3572

UniProt: P40189

Pathways: JAK-STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints