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Details for Product No. ABIN309612

Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (N-Term) antibody

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Antigen
Synonyms RIP3, Hcyp2, 2610528K09Rik, AW107945, Rip3, RIPK3
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Dog (Canine), Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN309612
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-RIPK3 antibody: synthetic peptide directed towards the N terminal of human RIPK3
Sequence GGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSF GILMWAVLAG
Predicted Reactivity Human : 100%, Dog : 92%, Horse : 85%, Mouse : 85%, Pig : 85%, Bovine : 78%
Characteristics This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name RIPK3
Background RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Molecular Weight 57kDa
Gene ID 11035
NCBI Accession NP_006862, NM_006871
UniProt Q9Y572
Research Area Apoptosis/Necrosis, Signaling
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-RIPK3 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Product cited in: Lazrek, Goffard, Schanen et al.: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, 2006 (PubMed).

Background publications Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Alternatives for antigen "Receptor-Interacting serine-threonine Kinase 3 (RIPK3)", type "Antibodies"
Hosts (61), (5)
Reactivities (51), (25), (12), (6), (5), (4), (4), (4), (1)
Applications (54), (18), (15), (14), (4), (4), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1)
Epitopes (8), (8), (5), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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