Amino-terminal Enhancer of Split (AES) antibody

Antigen: Amino-terminal Enhancer of Split (AES)

Synonyms: GRG, ESP1, GRG5, TLE5, AES-1, AES-2, Grg, Grg5, AL024115, MGC124620, AES, MGC64216, zgc:64216, aes, MGC68432, grg, esp1, grg5, tle5, aes-1, aes-2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine)

Application: Western Blotting (WB)

Catalog no.: ABIN309826

Additional Information

Alternative name: AES / ESP1

Gene ID: AES

UniProt: Q08117

Immunogen: The immunogen for anti-AES antibody: synthetic peptide directed towards the C terminal of human AES

Sequence: GLQPPSLPAVSAGTGLLSLSALGSQAHLSKEDKNGHDGDT HQEDDGEKSD

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 100 µl of distilled water. Final anti-AES antibody concentration is 1 mg/ml.

Description: AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genesThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

Characteristics: Antigen Size: 197 amino acids

Molecular Weight: 22kDa

Application Details

Application Notes: WB Suggested Anti-AES Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate.

Purification: Protein A purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-AES Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate

Publications

Product: Jan, Matter, Pai et al.: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, 2004 (PubMed).