Ring Finger Protein 8 (RNF8) antibody
| Antigen |
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| Synonyms |
FLJ12013, KIAA0646 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
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| Catalog no. |
ABIN309989 |
| Quantity |
0.1 mg |
| Price |
251.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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RNF8
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Gene ID
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RNF8
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UniProt
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O76064
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Immunogen
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The immunogen for anti-RNF8 antibody: synthetic peptide directed towards the C terminal of human RNF8
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Sequence
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MEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVL SHMNDVLENE
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Cross-Reactivity
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Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 100 µl of distilled water. Final anti-RNF8 antibody concentration is 1 mg/ml.
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Description
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RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Characteristics
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Antigen Size: 485 amino acids
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Molecular Weight
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55kDa
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Purification
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Protein A purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Research Area
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Proteolysis / Ubiquitin, Ion Channels
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Restrictions
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For Research Use only
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Product
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Lehner, Sanderson: "A protein interaction framework for human mRNA degradation." in: Genome research, Vol. 14, Issue 7, pp. 1315-23, 2004 (PubMed).
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Alternatives for antigen "Ring Finger Protein 8 (RNF8)", type "Antibodies"
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Hosts
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Rabbit (28), Goat (4), Mouse (1)
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Reactivities
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Human (32), Rat (Rattus) (21), Mouse (Murine) (19)
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Applications
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Western Blotting (WB) (17), Immunofluorescence (IF) (16), ELISA (13), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
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Epitopes
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C-Term (5), N-Term (2)
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2013 BioMed Central Research Awards
