RNF8 antibody (AA 335-364)

Catalog No. ABIN3032492

Product Details anti-RNF8 Antibody

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Binding Specificity: AA 335-364

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 335-364 from the human protein was used as the immunogen for this RNF8 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the RNF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RNF8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for RNF8

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Alternative Name: RNF8 (RNF8 Products)

Synonyms: hRNF8 antibody, 3830404E21Rik antibody, AIP37 antibody, RNF8 antibody, rnf8 antibody, fc66f09 antibody, wu:fc66f09 antibody, zgc:55936 antibody, zgc:77313 antibody, ring finger protein 8 antibody, ring finger protein 8, E3 ubiquitin protein ligase S homeolog antibody, ring finger protein 8, E3 ubiquitin protein ligase L homeolog antibody, ring finger protein 8, E3 ubiquitin protein ligase antibody, RNF8 antibody, Rnf8 antibody, rnf8.S antibody, rnf8.L antibody, rnf8 antibody

Background: The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response