ADAT1 antibody (C-Term)

Catalog No. ABIN310070

The Rabbit Polyclonal anti-ADAT1 antibody is suitable to detect ADAT1 in samples from Human, Mouse, Rat, Dog, Horse and Guinea Pig. It has been validated for WB and IHC.

Quick Overview for ADAT1 antibody (C-Term) (ABIN310070)

Target: ADAT1 (Adenosine Deaminase, tRNA-Specific 1 (ADAT1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ADAT1 Antibody

Binding Specificity: C-Term

Sequence: LFRSFQKLLS RIARDKWPHS LRVQKLDTYQ EYKEAASSYQ EAWSTLRKQV

Predicted Reactivity: Dog: 79%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ADAT1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 502 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAT1

Target: ADAT1 (Adenosine Deaminase, tRNA-Specific 1 (ADAT1))

Alternative Name: ADAT1

Background: ADAT1 is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, the family participates in the pre-mRNA editing of nuclear transcripts. ADAT1, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.
Alias Symbols: HADAT1
Protein Interaction Partner: UBC, ELAVL1,
Protein Size: 502

Molecular Weight: 55 kDa

Gene ID: 23536

NCBI Accession: NM_012091, NP_036223

UniProt: Q9BUB4