NKD1 antibody (N-Term)

Catalog No. ABIN310131

The Rabbit Polyclonal anti-NKD1 antibody (ABIN310131) specifically detects NKD1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog and Guinea Pig samples.

Quick Overview for NKD1 antibody (N-Term) (ABIN310131)

Target: NKD1 (Naked Cuticle Homolog 1 (NKD1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NKD1 Antibody

Binding Specificity: N-Term

Purpose: NKD1 Antibody - N-terminal region

Sequence: ELVGDVLRDT LSEEEEDDFR LEVALPPEKT DGLGSGDEKK MERVSEPCPG

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 85%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against NKD1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NKD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106203

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKD1

Target: NKD1 (Naked Cuticle Homolog 1 (NKD1))

Alternative Name: NKD1

Background:

Background Information: In the mouse, Nkd is a Dishevelled -binding protein that functions as a negative regulator of the Wnt-beta-catenin -Tcf signaling pathway.In the mouse, Nkd is a Dishevelled (see DVL1, MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1, MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM].

Gene Name: Naked cuticle homolog 1 (Drosophila)

Alternative Symbols: Naked1

Protein Name: Protein naked cuticle homolog 1

Molecular Weight: 52kDa

Gene ID: 85407

NCBI Accession: NP_149110

UniProt: Q969G9