Naked Cuticle Homolog 1 (Drosophila) (NKD1) antibody

Antigen: Naked Cuticle Homolog 1 (Drosophila) (NKD1)

Synonyms: Naked1, Nkd, 2810434J10Rik, 9030215G15Rik

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Chicken

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN310131

Additional Information

Alternative name: NKD1

Gene ID: NKD1

UniProt: Q969G9

Immunogen: The immunogen for anti-NKD1 antibody: synthetic peptide directed towards the N terminal of human NKD1

Sequence: ELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKK MERVSEPCPG

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 50 µl of distilled water. Final anti-NKD1 antibody concentration is 1 mg/ml.

Description: In the mouse, Nkd is a Dishevelled -binding protein that functions as a negative regulator of the Wnt-beta-catenin -Tcf signaling pathway.In the mouse, Nkd is a Dishevelled (see DVL1, MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1, MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM].

Characteristics: Antigen Size: 470 amino acids

Molecular Weight: 52kDa

Application Details

Purification: Affinity Purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) antibody

anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) antibody (Image 2)

Publications

Product: Yan, Wiesmann, Rohan et al.: "Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 14973-8, 2001 (PubMed).