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Antibodies
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anti-serine/threonine Kinase 11 (STK11) antibody
serine/threonine Kinase 11 (STK11) antibody
| Antigen |
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| Synonyms |
xeek1, Stk11, STK11, pjs, LKB1, XEEK1, wu:fj61a05, zgc:110180 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Zebrafish, Xenopus laevis, Chicken
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Conjugate
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Alexa Fluor 350 (5), Alexa Fluor 488 (5), Alexa Fluor 555 (5), Alexa Fluor 647 (5), PE,Cy5.5 (5), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB) (75), ELISA (58), Immunofluorescence (IF) (39), Immunohistochemistry (IHC) (33), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoprecipitation (IP) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN310216 |
| Quantity |
0.1 mg |
| Price |
251.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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STK11
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Gene ID
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STK11
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UniProt
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Q15831
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Immunogen
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The immunogen for anti-STK11 antibody: synthetic peptide directed towards the N terminal of human STK11
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Sequence
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TLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNV IQLVDVLYNE
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 100 µl of distilled water. Final anti-STK11 antibody concentration is 1 mg/ml.
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Description
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STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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Characteristics
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Antigen Size: 433 amino acids
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Molecular Weight
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48kDa
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Application Notes
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WB Suggested Anti-STK11 Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysate.
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Purification
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Protein A purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Xie, Dong, Zhang et al.: "Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells." in: The Journal of biological chemistry, Vol. 281, Issue 10, pp. 6366-75, 2006 (PubMed).
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Alternatives for antigen "serine/threonine Kinase 11 (STK11)", type "Antibodies"
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Hosts
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Rabbit (117), Mouse (5)
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Reactivities
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Human (118), Mouse (Murine) (83), Rat (Rattus) (47), Cow (Bovine) (34), Dog (Canine) (29), Horse (Equine) (29), Chicken (24), Pig (Porcine) (5), Monkey (3)
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Applications
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Western Blotting (WB) (75), ELISA (58), Immunofluorescence (IF) (39), Immunohistochemistry (IHC) (33), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoprecipitation (IP) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (5), Alexa Fluor 488 (5), Alexa Fluor 555 (5), Alexa Fluor 647 (5), PE,Cy5.5 (5), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
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Epitopes
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pSer334 (12), pSer428 (9), C-Term (7), pThr189 (6), Internal Region (5), N-Term (4), pThr363 (4), pSer334,Internal Region (3), pSer428,C-Term (3), pThr189,Internal Region (3), AA 1-433 (2), AA 84-101 (1), C-Term,AA 421-433 (1), N-Term,Ile29 (1), N-Term,Val34 (1), pSer307 (1), pThr505,pThr508 (1)
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2013 BioMed Central Research Awards
