RAD23 Homolog A (S. Cerevisiae) (RAD23A) antibody

Antigen: RAD23 Homolog A (S. Cerevisiae) (RAD23A)

Synonyms: HHR23A, MGC111083, HR23A, mHR23A, AL024030, 2310040P19Rik, zgc:92001, wu:fe11h06, RAD23A, MGC140027

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Rabbit

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN310302

Additional Information

Alternative name: RAD23A

Gene ID: RAD23A

UniProt: P54725

Immunogen: The immunogen for anti-RAD23A antibody: synthetic peptide directed towards the middle region of human RAD23A

Sequence: GIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQ FQNMRQVIQQ

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 100 µl of distilled water. Final anti-RAD23A antibody concentration is 1 mg/ml.

Description: RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Characteristics: Antigen Size: 363 amino acids

Molecular Weight: 40kDa

Application Details

Application Notes: WB Suggested Anti-RAD23A Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate.

Purification: Protein A purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-RAD23A Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate

anti-RAD23 Homolog A (S. Cerevisiae) (RAD23A) antibody (Image 2)

Publications

Product: Ju, Xie: "A synthetic defect in protein degradation caused by loss of Ufd4 and Rad23." in: Biochemical and biophysical research communications, Vol. 341, Issue 2, pp. 648-52, 2006 (PubMed).