Osteoactivin antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Dog (Canine)
Human (30), Mouse (Murine) (23), Rat (Rattus) (23), Cow (Bovine) (20), Pig (Porcine) (19), Guinea Pig (18), Horse (Equine) (18), Dog (Canine) (2), Cat (Feline) (1), Chicken (1), Xenopus laevis (1)
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
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| Catalog no. |
ABIN310605 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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GPNMB / HGFIN
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Gene ID
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GPNMB
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UniProt
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A8K7R3
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Immunogen
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The immunogen for anti-GPNMB antibody: synthetic peptide directed towards the N terminal of human GPNMB
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Sequence
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DENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPAL VGSNITFAVN
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-GPNMB antibody concentration is 1 mg/ml.
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Description
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GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
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Characteristics
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Antigen Size: 560 amino acids
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Molecular Weight
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60kDa
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Oh, Yang, Hahn et al.: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, 2005 (PubMed).
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Alternatives for antigen "Osteoactivin", type "Antibodies"
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Hosts
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Rabbit (30), Mouse (3)
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Reactivities
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Human (30), Mouse (Murine) (23), Rat (Rattus) (23), Cow (Bovine) (20), Pig (Porcine) (19), Guinea Pig (18), Horse (Equine) (18), Dog (Canine) (2), Cat (Feline) (1), Chicken (1), Xenopus laevis (1)
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Applications
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ELISA (16), Immunofluorescence (IF) (16), Flow Cytometry (FACS) (15), Western Blotting (WB) (14), Immunohistochemistry (IHC) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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AA 551-568 (3), N-Term (3)
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