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NDRG Family Member 2 (NDRG2) antibody

Antigen

NDRG Family Member 2 (NDRG2)

Synonyms SYLD, FLJ25522, KIAA1248, DKFZp781G1938, ndrg2, MGC53937, MGC79559, NDRG2, MGC128884, DKFZp459G2119
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Pig (Porcine), Dog (Canine)

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
1 reference available
Catalog no. ABIN310960
Quantity 50 µg
Price 317.90 $   Plus shipping costs $45.00
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Additional Information

Alternative name NDRG2
Gene ID NDRG2
Immunogen The immunogen for anti-NDRG2 antibody: synthetic peptide directed towards the C terminal of human NDRG2
Sequence GYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSE SGTLSSGPPG
Cross-Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Format Lyophilized
Reconstitution Add 50 µl of distilled water. Final anti-NDRG2 antibody concentration is 1 mg/ml.
Description NDRG2¡¯s gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Characteristics Antigen Size: 357 amino acids
Molecular Weight 39kDa

Application Details

Application Notes WB Suggested Anti-NDRG2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate.
Purification Affinity Purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Cancer, Alzheimer's Disease
Restrictions For Research Use only

Publications

Product Lusis, Watson, Chicoine et al.: "Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma." in: Cancer research, Vol. 65, Issue 16, pp. 7121-6, 2005 (PubMed).

Alternatives

Alternatives for antigen "NDRG Family Member 2 (NDRG2)", type "Antibodies"
Hosts Rabbit (35), Mouse (3), Goat (2)
Reactivities Human (36), Rat (Rattus) (29), Mouse (Murine) (28), Dog (Canine) (20), Chicken (19), Horse (Equine) (18), Pig (Porcine) (18), Cat (Feline) (1), Cow (Bovine) (1)
Applications Western Blotting (WB) (26), ELISA (18), Immunofluorescence (IF) (16), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (2), N-Term (2), Center (1), Internal Region (1)