OAT antibody

Antigen: OAT

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Chicken, Pig (Porcine)

Application: Western Blotting (WB)

Catalog no.: ABIN310979

Additional Information

Gene ID: OAT

UniProt: P04181

Immunogen: The immunogen for anti-OAT antibody: synthetic peptide directed towards the C terminal of human OAT

Sequence: VRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGD IIRFAPPLVI

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 100 µl of distilled water. Final anti-OAT antibody concentration is 1 mg/ml.

Description: OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy.This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB459793.1 27-68 43-2062 BC016928.1 1-2020 2063-2066 M12267.1 2010-2013

Characteristics: Antigen Size: 439 amino acids

Molecular Weight: 45kDa

Application Details

Application Notes: WB Suggested Anti-OAT Antibody Titration: 5.0ug/ml
Positive Control: HepG2 cell lysate.

Purification: Protein A purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-OAT Antibody Titration: 5.0ug/ml
Positive Control: HepG2 cell lysate

Publications

Product: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).