OAT antibody (AA 160-439)

Catalog No. ABIN6144985

Product Details anti-OAT Antibody

Target: OAT (Ornithine Aminotransferase (OAT))

Binding Specificity: AA 160-439

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: VKGIQKYKAK IVFAAGNFWG RTLSAISSST DPTSYDGFGP FMPGFDIIPY NDLPALERAL QDPNVAAFMV EPIQGEAGVV VPDPGYLMGV RELCTRHQVL FIADEIQTGL ARTGRWLAVD YENVRPDIVL LGKALSGGLY PVSAVLCDDD IMLTIKPGEH GSTYGGNPLG CRVAIAALEV LEEENLAENA DKLGIILRNE LMKLPSDVVT AVRGKGLLNA IVIKETKDWD AWKVCLRLRD NGLLAKPTHG DIIRFAPPLV IKEDELRESI EIINKTILSF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-439 of human OAT (NP_000265.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-OAT antibody (ABIN6144985)

Zeng, Yang, Du, Li, Shen, Liu, Chen, Kamal, Guan, Cheng, Wang, Xu: "Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats." in: Oncotarget, Vol. 8, Issue 60, pp. 102020-102032, (2017) (PubMed).

Target Details for OAT

Target: OAT (Ornithine Aminotransferase (OAT))

Alternative Name: OAT (OAT Products)

Synonyms: 151832_at antibody, CG8782 antibody, Dmel\\CG8782 antibody, hoga antibody, AI194874 antibody, rOAT antibody, GACR antibody, HOGA antibody, OATASE antibody, OKT antibody, Ornithine aminotransferase precursor antibody, ornithine aminotransferase, gene 1 antibody, ornithine aminotransferase antibody, Oat antibody, oat.1 antibody, OAT antibody, Lbys_2951 antibody, Riean_0998 antibody, Ftrac_2019 antibody, Celal_2605 antibody, Deipr_1149 antibody, Celly_0230 antibody, Weevi_2065 antibody, Fluta_4071 antibody, Halhy_2848 antibody, Theth_0565 antibody, oat antibody

Background: This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.,OAT,GACR,HOGA,OATASE,OKT,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,Neuroscience,OAT

Molecular Weight: 32 kDa/48 kDa

Gene ID: 4942

UniProt: P04181