PDZ Binding Kinase (PBK) antibody
| Antigen |
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| Synonyms |
SPK, CT84, TOPK, Nori-3, FLJ14385, AW538537, D14Ertd732e, 2810434B10Rik, topk, zgc:92050, PBK, MGC165897 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Dog (Canine), Pig (Porcine), Zebrafish
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Conjugate
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Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
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Application
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ELISA (46), Western Blotting (WB) (43), Immunofluorescence (IF) (35), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22), Immunohistochemistry (IHC) (12), Flow Cytometry (FACS) (4), Immunocytochemistry (ICC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (2), Dot Blot (DB) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN311092 |
| Quantity |
50 µg |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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PBK / TOPK
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Gene ID
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PBK
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UniProt
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Q96KB5
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Immunogen
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The immunogen for anti-PBK antibody: synthetic peptide directed towards the N terminal of human PBK
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Sequence
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SLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALN MARGLKYLHQ
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-PBK antibody concentration is 1 mg/ml.
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Description
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PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Characteristics
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Antigen Size: 322 amino acids
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Molecular Weight
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36kDa
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Application Notes
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WB Suggested Anti-PBK Antibody Titration: 0.2-1 ug/ml
Positive Control: 721_B cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).
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Alternatives for antigen "PDZ Binding Kinase (PBK)", type "Antibodies"
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Hosts
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Rabbit (60), Mouse (12)
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Reactivities
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Human (71), Mouse (Murine) (28), Rat (Rattus) (27), Cow (Bovine) (19), Dog (Canine) (19), Pig (Porcine) (18), Cat (Feline) (1), Chicken (1)
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Applications
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ELISA (46), Western Blotting (WB) (43), Immunofluorescence (IF) (35), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22), Immunohistochemistry (IHC) (12), Flow Cytometry (FACS) (4), Immunocytochemistry (ICC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (2), Dot Blot (DB) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
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Epitopes
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pThr9 (8), C-Term (5), N-Term (4), Tyr74 (2), pTyr74 (2), C-Term,Cys300 (1), Met11 (1), Met12 (1), N-Term,Asn6 (1), pThr163 (1)
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2013 BioMed Central Research Awards
