PBK antibody (N-Term)

Catalog No. ABIN1881635

There are 2+ publications for this product available. The Rabbit Polyclonal anti-PBK antibody is suitable to detect PBK in samples from Human and Mouse. It has been validated for WB, IHC (p) and FACS.

Quick Overview for PBK antibody (N-Term) (ABIN1881635)

Target: PBK (PDZ Binding Kinase (PBK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB40570

Product Details anti-PBK Antibody

Binding Specificity: AA 58-86, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Pbk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of mouse Pbk.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PBK antibody (ABIN1881635)

Zykova, Zhu, Lu, Higgins, Tatsumi, Abe, Bode, Dong: "Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 23, pp. 6884-93, (2006) (PubMed).

Fujibuchi, Abe, Takeuchi, Ueda, Shigemoto, Yamamoto, Kito: "Expression and phosphorylation of TOPK during spermatogenesis." in: Development, growth & differentiation, Vol. 47, Issue 9, pp. 637-44, (2005) (PubMed).

Target Details for PBK

Target: PBK (PDZ Binding Kinase (PBK))

Alternative Name: Pbk

Background: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity).

Molecular Weight: 36745

NCBI Accession: NP_075698

UniProt: Q9JJ78