Junctophilin 2 antibody (Middle Region)
-
- Target See all Junctophilin 2 (JPH2) Antibodies
- Junctophilin 2 (JPH2)
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Junctophilin 2 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- ANQESNIART LARELAPDFY QPGPEYQKRR LLQEILENSE SLLEPPDRGA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against JPH2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human JPH2
- Top Product
- Discover our top product JPH2 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 696 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Junctophilin 2 (JPH2)
- Alternative Name
- JPH2 (JPH2 Products)
- Synonyms
- CMH17 antibody, JP-2 antibody, JP2 antibody, jp antibody, 1110002E14Rik antibody, Jp2 antibody, junctophilin 2 antibody, junctophilin-2 antibody, JPH2 antibody, LOC100461095 antibody, LOC610874 antibody, Jph2 antibody
- Background
-
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH2 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
Alias Symbols: FLJ40969, JP-2, JP2, CMH17
Protein Interaction Partner: CAV3, E2F4,
Protein Size: 696 - Molecular Weight
- 74 kDa
- Gene ID
- 57158
- NCBI Accession
- NM_020433, NP_065166
- UniProt
- Q9BR39
-