Tubulin, Alpha, 3C (TUBA3C) (N-Term) antibody

Details for Product No. ABIN311613
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Antigen
Synonyms TUBA3C, TUBA3D, TUBA2, bA408E5.3, TUBA1A, TUBA3, TUBA4A
Epitope
N-Term
(8), (7), (6), (2), (2), (2)
Reactivity
Mouse (Murine), Rat (Rattus), Caenorhabditis elegans (C. elegans), Fruit Fly (Drosophila melanogaster), Human
(20), (5), (5), (1), (1)
Host
Rabbit
(15), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(20), (14), (4), (3)
Pubmed 1 reference available
Quantity 50 µg
Options
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Catalog No. ABIN311613
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Immunogen Synthetic peptide directed towards the N terminal of human TUBA3C
Sequence VDLEPTVVDE VRTGTYRQLF HPEQLITGKE DAANNYARGH YTIGKEIVDL
Predicted Reactivity African clawed frog : 100 %
Characteristics This is a rabbit polyclonal antibody against TUBA3C. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TUBA3C
Background Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome.
Molecular Weight 50 kDa
Gene ID 7278
NCBI Accession NM_006001, NP_005992
UniProt Q13748
Research Area Signaling, Cytoskeleton
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 450 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Tubulin, Alpha, 3C (TUBA3C) (N-Term) antibody WB Suggested Anti-TUBA3C Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Background publications Jin, Smith, Stark et al.: "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization." in: Current biology : CB, Vol. 14, Issue 16, pp. 1436-50, 2004 (PubMed).

Validation Images
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