TNFRSF4 antibody (FITC)

Catalog No. ABIN316461

Product Details anti-TNFRSF4 Antibody (FITC)

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Reactivity: Human, Cat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Characteristics: Synonyms: OX40L receptor, ACT35 antigen, TXGP1L, Tumor necrosis factor receptor superfamilymember 4, TAX transcriptionally-activated glycoprotein 1 receptor

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Immunogen: CHO-derived feline CD134-Fc fusion protein.

Clone: 7D6

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: 1/5, use 10 μL of the suggested working dilution to label 1x10^6 cells in100l.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Alternative Name: CD134 / TNFRSF4 (TNFRSF4 Products)

Background: CD134 is a 43 kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.Synonyms: ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, TXGP1L, Tumor necrosis factor receptor superfamily member 4

UniProt: P43489

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints