ZAP70 antibody (AA 280-309) (FITC)

Catalog No. ABIN316507

The FITC-conjugated Mouse Monoclonal anti-ZAP70 antibody (Clone SBZAP) (ABIN316507) specifically detects ZAP70 in EIA. The antibody is reactive with Human samples.

Quick Overview for ZAP70 antibody (AA 280-309) (FITC) (ABIN316507)

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZAP70 antibody is conjugated to FITC

Application: Enzyme Immunoassay (EIA)

Clone: SBZAP

Product Details anti-ZAP70 Antibody (FITC)

Binding Specificity: AA 280-309

Specificity: This antibody recognises ZAP-70.

Characteristics: Synonyms: ZAP-70, ZAP 70, SRK, 70 kDa zeta-associated protein, Syk-related tyrosine kinase

Immunogen: Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated toKLH

Isotype: IgG1

Application Details

Application Notes: Flow cytometry (membrane permeabilisation is required).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: BPS containing 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ZAP70

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Alternative Name: ZAP70

Background: ZAP 70 is a 70 kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.Synonyms: 70 kDa zeta-associated protein, SRK, Syk-related tyrosine kinase, ZAP 70, ZAP-70

Gene ID: 7535

UniProt: P43403

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway